La Costa Resort and Spa is at the top of my list because the Chopra Center for Well Being is there. I'm a huge fan of Deepak Chopra's work. Just driving by the spa puts you in a relaxing mood!
Cal-a-Vie is located just north of San Diego in the hillsides of Vista. They offer vacation spa packages so that you can relax and revitalize your mind, body, and spirit! It was voted #1 destination spa for programs and settings by Conde Naste Traveler Magazine.
I love to hang out in downtown San Diego, so Spa Velia is a choice if I do decide to go with a day spa. DaySpa Magazine gave Spa Velia the Diamond Day Spa of the Year Award in 2007. I like that I can go have lunch at one of the many restaurants downtown afterwards ;)